The Effect of Childhood Maltreatment on College Students’ Depression: The Role of Neurotic Personality and MAOA Gene rs3027407 Polymorphism

Abstract

Abstract: To investigate the relationship and internal mechanism of childhood maltreatment, neurotic personality, MAOA gene rs3027407 polymorphism and depression among college students, a total of 311 college students were recruited in the current study. After given informed consents, they completed the Chinese Version of Childhood Trauma Questionnaire, Center for Epidemiological Studies Depression Scale (CES-D) and Eysenck Personality Questionnaire - the Neurotic Subscale. And DNA typing was performed after blood sampling by professional nurses. The results showed that: 1) childhood maltreatment, neurotic personality and college students’ depression were positively and significantly correlated with each other; 2) the effect of childhood maltreatment on depression in college students was almost fully mediated by neurotic personality; 3) MAOA gene rs3027407 polymorphism moderated the effect of neurotic personality on college students’ depression.

Key words: childhood maltreatment, neurotic personality, college students’ depression, MAOA gene

摘要： 探讨儿童期受虐经历、神经质人格、MAOA基因rs3027407多态性与大学生抑郁之间的关系及内在作用机制，以311名大学生为研究对象使用流调中心抑郁量表、中文版儿童期虐待量表和艾森克人格问卷神经质分量表，并由专业护士对其抽取血液后进行DNA分型。结果表明：（1）儿童期受虐经历、神经质人格及大学生抑郁均呈显著正相关；（2）神经质人格在儿童期受虐经历与大学生抑郁的影响中起完全中介作用；（3）MAOA基因rs3027407多态性调节该中介模型后半段。

关键词: 儿童期受虐经历, 神经质人格, 大学生抑郁, MAOA基因

CLC Number:

B844

PENG Liyi, HU Yiqiu, ZENG Zihao, ZHAN Lin. The Effect of Childhood Maltreatment on College Students’ Depression: The Role of Neurotic Personality and MAOA Gene rs3027407 Polymorphism[J]. Studies of Psychology and Behavior, 2021, 19(2): 230-236.

彭丽仪, 胡义秋, 曾子豪, 詹林. 儿童期受虐经历对大学生抑郁的影响：神经质人格和MAOA基因rs3027407多态性的作用[J]. 心理与行为研究, 2021, 19(2): 230-236.

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