非情绪与情绪背景下行为抑制时外侧前额叶的功能分化：一项fNIRS研究*

摘要/Abstract

摘要： 采用功能性近红外脑成像技术（fNIRS），结合事件相关设计，在非情绪与情绪背景下，测量个体完成go/no-go任务时外侧前额叶皮层氧合血红蛋白浓度（HbO）的变化。结果发现：在非情绪背景下，行为抑制时双侧背外侧前额叶皮层和右眶额叶皮层负激活；在情绪背景下，行为抑制时双侧背外侧前额叶皮层和眶额皮层负激活，情绪与行为抑制的交互作用显著负激活双侧腹外侧前额叶皮层。结果表明：在非情绪与情绪背景下，双侧背外侧前额叶和右眶额叶皮层可能以神经抑制的活动形式参与行为抑制反应；腹外侧前额叶皮层可能不是行为抑制的重要脑区，但对情绪与行为抑制整合具有重要意义，特别是在负性情绪背景下，双侧腹外侧前额叶皮层可能以更大程度的神经抑制活动参与到情绪与行为抑制交互作用中来。

关键词: 非情绪背景, 情绪背景, 行为抑制, 外侧前额叶, fNIRS

Abstract: The right inferior frontal gyrus is generally considered a critical region for response inhibition. Recent studies, however, suggest that the role of this cortical area in response inhibition may be overstated and that the contributions of other regions of the prefrontal cortex(PFC)are often overlooked. To identify regions of the prefrontal cortex beyond the right inferior frontal gyrus which may serve to support response inhibition, the present study used fNIRS to record the change of oxygenated hemoglobin concentration of the lateral PFC, when our college students(right-handed)completed the go/no-go task under the non-emotional and the emotional contexts. As a result, under the non-emotional context, during response inhibition, the oxygenated hemoglobin concentration decreased in the bilateral dorsolateral prefrontal cortex(DLPFC)and the right orbito-frontal cortex(OFC); under the emotional context, the oxygenated hemoglobin concentration in the DLPFC and the bilateral ventrolateral prefrontal cortex(VLPFC)and OFC significantly deactivated. These results suggested that under the non-emotional and emotional context, bilateral DLPFC may work in behavioral inhibition in the form of neural activity inhibition. The VLPFC may not be the important area of behavioral inhibition, but the bilateral VLPFC is very important in the integration of emotional and behavioral control especially in the background of negative emotions. The VLPFC may be in the form of a greater degree of neural activity inhibition to finish the inhibition task.

Key words: non-emotional context, emotional context, behavior control, the lateral prefrontal cortex, functional near-infrared spectroscopy(fNIRS).

中图分类号:

B842.6

白学军,刘颖,章鹏,张琪涵. 非情绪与情绪背景下行为抑制时外侧前额叶的功能分化：一项fNIRS研究*[J]. 心理与行为研究, 2015, 13(5): 606-613.

Bai Xuejun, Liu Ying, Zhang Peng, Zhang Qihan. The Functional Differentiation of the Lateral Prefrontal on the Behavior Control in the Context of Emotional and Non-emotional: A fNIRS Study[J]. Studies of Psychology and Behavior, 2015, 13(5): 606-613.

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