The Brain Gray Matter Basis of the Decline of Global Motion Sensitivity in Elderly Adults

Abstract

Abstract: Using multi-voxel pattern analysis (MVPA) and random dots kinematograms paradigm, the relationship between the decline of global motion sensitivity (GMS) and the decline of brain gray matter volume in the elders was investigated. The results showed that, compared to young adults, the GMS and the gray matter volume in V5/MT, V3, and the frontal and parietal regions were significantly lower in elderly adults; the gray matter volume in V5/MT and V3 could efficiently predict individual’s GMS. The results suggested that the decline of the gray matter volume in V5/MT, V3, and especially V3 may account for a substantial part of the decline of GMS in elderly adults. And the decline of GMS may be somewhat due to the decline of gray matter volume in other brain regions based on “dedifferentiation hypothesis”.

Key words: aging of global motion perception, gray matter volume, multi-voxel pattern analysis, V5/MT, V3

摘要： 本研究使用多体素模式分析方法和随机点阵范式，首次探索了老年人整体运动敏感性（GMS）下降和其脑灰质体积下降间的关系。结果发现，老年人GMS显著低于年轻人，老年人V5/MT、V3和额顶等脑区灰质体积显著小于年轻人；V5/MT和V3区的灰质体积信号可以有效预测个体的GMS。结果提示，V5/MT区和V3区，特别是V3区的灰质体积下降可能是老年人GMS下降的主要原因；而基于“去分化假设”，全脑范围内其余脑区的灰质体积下降可能也在一定程度上与老年人GMS下降有关。

关键词: 整体运动知觉老化, 灰质体积, 多体素模式分析, V5/MT, V3

CLC Number:

B842

JIN Hua, ZHU Ziliang, YAN Shizhen, LIANG Ziping, AIKEDAN Aisikaer, YIN Jianzhong, JIANG Yunpeng, LIN Lin. The Brain Gray Matter Basis of the Decline of Global Motion Sensitivity in Elderly Adults[J]. Studies of Psychology and Behavior, 2020, 18(5): 603-610.

金花, 朱子良, 严世振, 梁紫平, 艾克旦 ? 艾斯卡尔, 尹建忠, 姜云鹏, 林琳. 老年人整体运动敏感性降低的脑灰质体积变化基础[J]. 心理与行为研究, 2020, 18(5): 603-610.

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